Thermo Scientific Vanquish Online 2D-LC Systems are application specific instruments that improve the analysis of complex samples and simplify the separation of difficult-to-resolve analytes. There are four configurations available, focused on online SPE or various heart-cutting two-dimensional liquid chromatography (LC-LC) workflows. The modular instrument can use modules from the Vanquish Core HPLC, Vanquish Flex UHPLC or Vanquish Horizon UHPLC systems, retaining the performance, robustness, and ease of use of the Vanquish platform, while offering maximum application flexibility.
Application specific options:
Vanquish Online SPE HPLC and UHPLC Systems
The Thermo Scientific Vanquish Online SPE HPLC and UHPLC Systems ensures confidence in complex sample analysis. They perform analyte pre-concentration and sample clean-up using an automated, repeatable workflow, in addition saving solvent and time compared to offline sample preparation steps. The system is configured using modules from the Vanquish Core HPLC, Vanquish Flex UHPLC or Horizon UHPLC systems, retaining all the performance, robustness and ease of use of the Vanquish LC platform.
Vanquish Loop Heart-Cut 2D-LC Systems
The Thermo Scientific Vanquish Loop Heart-Cut 2D-LC System increases confidence in peak purity. This two-dimensional LC system (LC-LC) enables collecting one or multiple fractions of the first-dimension separation in a sample loop and transferring the cut-out fraction(s) in an automated workflow to a second-dimension separation. Heart-Cut 2D-LC can reveal hidden impurities that co-elute with the analytes of interest by using two complementary column chemistries to gain more separation power. The system is configured using modules from the Vanquish Core HPLC, Vanquish Flex UHPLC or Horizon UHPLC systems, retaining all the performance, robustness and ease of use of the Vanquish LC platform.
Vanquish Trap Heart-Cut 2D-LC Systems
The Thermo Scientific Vanquish Trap Heart-Cut 2D-LC System achieves in-depth analysis for greater confidence in peak purity and identity. This two-dimensional LC (LC-LC) system enables collecting a single fraction of the first-dimension separation onto a trap column to pre-concentrate, and achieving mobile phase compatibility for transferring the fraction for a second-dimension separation or compatibility between UV and MS detection. Heart-cut 2D-LC can reveal hidden impurities that co-elute with the analytes of interest by applying two complementary column chemistries to gain more separation power. The system is configured using modules from the Vanquish Flex UHPLC or Horizon UHPLC systems, delivering performance, robustness and ease of use of the Vanquish LC platform.
Vanquish Simple Switch 2D-LC Systems
The innovative Thermo Scientific Vanquish Simple Switch 2D-LC System enables seamless switching between a trap heart-cut 2D-LC system and a dual LC system. This two-dimensional LC (LC-LC) system is an innovative, all-in-one system that uses the novel Thermo Scientific Vanquish Dual Split Sampler to provide users with a seamless switch between both system capabilities, without re-plumbing. This system supplies the confidence and productivity you need regardless of which task needs to be performed.
