The new Thermo Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer excels in the most challenging applications, including low level PTM analysis, multiplexed relative quantitation using isobaric tags, intact protein characterization, and MSn analysis of small molecules. This system incorporates the brightest ion source, a segmented quadrupole mass filter with improved selectivity and ion transmission, Advanced Vacuum Technology for improved ion transmission to the Orbitrap mass analyzer, and ETD HD, a higher-capacity ETD fragmentation. Moreover, latest innovations include the Advanced Peak Determination (APD) algorithm for improved data-dependent experiments and two new hardware options: UVPD, a new fragmentation technique achieved with a 213 nm UV laser and 1M, that provides 1,000,000 FWHM ultra-high resolution for improved structural elucidation and quantitation of isobaric compounds.
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