In situ observation of structure dynamics at nanostructure-characteristic length scales is extremely important if the focus is on the atomic-scale research. The Thermo Scientific Themis ETEM builds on the proven Titan Environmental Transmission Electron Microscope (ETEM) concept by combining both standard S/TEM (TEM and scanning transmission electron microscopy (STEM)) and dedicated environmental TEM capabilities for time-resolved, in situ studies of the dynamic behavior of nanomaterials. The Themis ETEM is designed as a fully integrated platform for in situ experiments, e.g. exposing nanostructures to gaseous reaction/operating environments.